Progressing Beyond Static Structural GPCR Understanding
Time: 10:00 am
day: Day One
Details:
- Strategies to engineer, express, and purify (orphan) GPCRs
- Using cryo-EM to solve small molecule-bound GPCR structures in multiple complexes to progress structure-based drug discovery
- Achieving strong molecular dynamic understanding using experimental structures in tandem with computational modelling techniques
