Irina Tikhonova

Company: Queen’s University Belfast

Job title: Reader

Seminars:

Computational Protocols for Prediction of GPCR Allosteric Sites 3:00 pm

Probe confined dynamic mapping protocols for allosteric site prediction Case studies for mapping extracellular, intracellular and interface allosteric sites Experimental validation of in silico protocolsRead more

day: Pre Conference Focus Day

Panel Discussion: Biased Signaling: From Pharmacology to Physiology 12:00 pm

GPCR signaling can be activated in a ‘biased’ response, via G proteins or β-arrestins with distinct biochemical and physiological actions from each other. The current field however requires further clarity to evaluate biased signaling from pharmacology to physiology for the benefit of discovering biologically relevant GPCR targets. From determining bias specificity to rationally designing biased…Read more

day: Pre Conference Focus Day