John McCorvy

Company: Medical College of Wisconsin

Job title: Assistant Professor

Seminars:

Structure-Based Approaches to Designing Biased Ligands 9:30 am

Leveraging structures toward identifying new chemotypes Using biophysical approaches toward understanding mechanisms of biased agonism Applying biased agonists as tools toward drug development to find new therapeutic indicationsRead more

day: Day One

Panel Discussion: Biased Signaling: From Pharmacology to Physiology 12:00 pm

GPCR signaling can be activated in a ‘biased’ response, via G proteins or β-arrestins with distinct biochemical and physiological actions from each other. The current field however requires further clarity to evaluate biased signaling from pharmacology to physiology for the benefit of discovering biologically relevant GPCR targets. From determining bias specificity to rationally designing biased…Read more

day: Pre Conference Focus Day