Stacey Southall

Stacey Southall

Company: Sosei Heptares

Job title: Director - Biophysics / Cryo-EM

Seminars:

Panel Discussion: Leveraging Human Genetics for Hit-to-Lead Optimization & Effective GPCRTarget Discovery 2:30 pm

Creating target discovery platforms based on genetic human data for better hit-to-lead optimization is at the forefront of early drug discovery pipelines across biotech and pharma industries. We will explore the learnings from Regeneron’s key candidate GPR75 and how to inform, develop and expedite the drug discovery process for clinical success. Leveraging the UK Biobank…Read more

day: Day One

Cryo-EM in GPCR Structure-Based Drug Discovery 11:30 am

Cryo-EM is a valuable method adding to the repertoire of biophysical and structural techniques for GPCR structure based drug discovery Exploitation of cryo-EM is now providing additional opportunities to solve structures of GPCRs for which limited tool ligands are available, which we will exemplify with cryo-EM enabled GPCR SBDD case studies Cryo-EM has improved accessibility…Read more

day: Day One

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