Welcome to the GPCRs - Targeted Drug Discovery Summit 2022!

Unlocking the Next Wave of Clinically Relevant GPCR Targets

Built with biopharmaceutical industry insights, this in person conference will bring together key opinion leaders to delve deep into the challenges associated with leveraging new structural data, explore emerging technologies and accelerate hit-to-lead optimization to successfully drug the next generation of GPCR targets with validated therapeutic relevance.

With 25+ pioneering speakers from large pharma, innovative biotech, and KOLs of academia who are shaping the landscape of GPCR drug discovery for the scientific community worldwide, join us in Boston to hear how they address the major challenges facing the industry:


Optimize Screening & Modeling Tools to Enhance GPCR Pharmacology & Drug Design

With effective screening & modeling for successful identification of GPCR targets remaining a key challenge in the field, immerse yourself in the advanced screening platforms & technologies to streamline your GPCR drug discovery efforts, with insights from Abalone Bio, Mebias Discovery & Octant


Explore the Latest Advancements in GPCR Structure-Based Drug Design to Improve Ligand-Receptor Affinity

Delve into pioneering ways to capture GPCR complexes with higher resolution to solve structures of GPCRs for which limited tool ligands are available with insights from Sosei Heptares, OMass Therapeutics, Medical College of Wisconsin & University of Toronto


Discover the Expansion of GPCR-Targeting Modalities Beyond Traditional Small Molecules

As the industry continues to advance in GPCR therapeutics, it is becoming more important than ever to drug high value candidates with increased target specificity & efficacy. Hear expert insights into the hottest modalities from Tectonic Therapeutic, Domain
Therapeutics & Confo Therapeutics


Tune into How Companies are Leveraging Human Genetics for Hit-to-Lead Optimization of More Effective GPCR Targeted Drugs

With the recent success of discovery platforms based on human genetic data for better hit-to-lead optimization, hear from companies like Orion Biotechnology & Pathios Therapeutics on the emerging strategies to inform & expedite
the drug discovery process towards clinical success


Discover Methods to Delineate GPCR Signaling Pathway Cross-talk for Novel Druggable Paradigms

Developing treatments for complex diseases requires understanding the complexity of receptor & signaling pathways. Hear first-hand from Eli Lilly & heptOME at our deep dive focus day on how to unravel the complexities of GPCR signaling mechanisms, bias signaling & allosteric modulation with therapeutic relevance

Health & Safety

The health, safety and well-being of our community remains our highest priority, therefore, all attendees will be required to complete a health declaration prior to attending the event, as well as comply with the City of Boston’s B Together policy. This policy requires individuals to show you proof of vaccination against COVID-19 in order to gain admittance to the conference venue. For further information around Health and Safety onsite, please visit our FAQs page here or for more information on the B Together Policy, please see here.

* Please note, this is subject to change at any time without prior notice.

Expert Speakers Include

Christel Menet


Confo Therapeutics

Christian Cortis


Tectonic Therapeutic

Francis Willard

Research Advisor

Eli Lilly

Graeme Milligan

Professor of Biochemistry

University of Glasgow

Xavier Leroy


Domain Therapeutics

Josephine Cardarelli


GPCR Therapeutics

Leon Chan

Head of Biology


M. Madan Babu

Chair of Biological Data Science

St Jude Children’s Research Hospital

Stacey Southall

Director - Biophysics / Cryo-EM

Sosei Heptares

Uli Stilz


Novo Nordisk Bio Innovation Hub

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