Integrating Machine Learning with Large-Scale Activity Measurements by Engineered Cells to Discover and Design GPCR-Activating Antibodies
Time: 2:45 pm
day: Pre-Conference Focus Day
Details:
- Implementing distributed activity measurement using FAST engineered cells to identify antibodies that activate GPCRs
- Running data through the FAST machine learning workflow to learn the sequencefunction landscape and then validating discovered and generated candidates
- Focusing on function and purposefully not optimizing for affinity, especially up front in the discovery process, can be a way to uncover GPCR activating antibodies
