Trans-Synaptic Allosteric Modulators of mGluR Pharmacology in Neurological Disease
Time: 2:30 pm
day: Conference Day One
Details:
- Synaptic adhesion molecules interface with GPCRs and allosterically modulate their pharmacological properties
- Disruption of these molecules lead to neuropsychiatric and neurodevelopmental consequences in animal models and humans
- Targetting these GPCRs, or the interface between GPCRs and synaptic adhesion molecules, may represent a new direction in pharmacological strategies
