Cesare Orlandi
Company: University of Rochester Medical Center
Job title: Assistant Professor
Seminars:
Afternoon Chair: 12:59 pm
day: Conference Day One
Unlocking Strategies to Identify Ligands that Activate Orphan GPCRs to Develop Agonists 9:00 am
Developing and optimizing novel methods to identify endogenous and synthetic ligands acting on GPCRs to allow for the design of targeted GPCR therapies Application of the novel Gz-Enhanced Signal Transduction assaY (GzESTY) for identifying orphan GPCR ligands in complex tissue extracts and compound libraries Development of novel screening assays for the rapid identification of inverse…Read more
day: Conference Day Two
Fireside Chat: Uncovering Tools to Discover Synthetic Ligands for Orphan GPCRs to Advance the Development of Effective Therapies 9:30 am
How to begin tackling orphan receptors with little known pharmacology to discover their functional roles? What tools do we have to identify the signaling pathways, downstream effects, and mechanisms of action of orphan GPCRs to understand their therapeutic relevance? Is there a need to always discover a ligand against an orphan GPCR and can we…Read more
day: Conference Day Two
Chair’s Closing Remarks & End of Conference Day One 4:00 pm
day: Conference Day One