Laurent Sabbagh
Scientific Director Domain Therapeutics
Laurent Sabbagh holds a Ph.D. in immunology from McGill University and undertook post-doctoral fellowships at the Ontario Cancer Institute and the University of Toronto before being recruited by University of Montreal as an assistant professor focusing his research on immunological memory, inflammation, and hematological malignancies. Subsequently, he led biomarker discovery efforts for inflammatory bowel disease and small molecules drug discovery programs for polycystic kidney disease at Vertex Pharmaceuticals. Laurent further led drug discovery programs for inflammatory disorders and cancer at Paraza Pharma Inc. Currently, he is Scientific Director at Domain Therapeutics leading drug discovery efforts of new molecules and antibodies targeting G protein-coupled receptors (GPCRs) in immuno-oncology, inflammation, and metabolic disorders.
Seminars
- Presenting Phase 1 outcomes, including safety data, dose-escalation results and the establishment of the Phase 2 dosing regimen
- Highlighting our translational biomarker strategy, including target-engagement readouts and how these biomarkers support Phase 2 readiness
- Outlining the Phase 2 clinical plan in sarcoma, detailing study rationale and how PK/PD and exposure–response insights inform the development approach
