Challenging GPCR Assumptions to Strengthen Confidence in Target Validation & Mechanism of Action
9:30 am - Wednesday 3rd March 2027
- Investigating how incomplete biological understanding can lead to incorrect conclusions about GPCR target engagement and therapeutic activity
- Applying modern pharmacology tools and experimental approaches to distinguish genuine biology from misleading assay outputs
- Sharing case studies that demonstrate the importance of validating mechanism, target engagement and translational relevance before advancing programs
