Decoding Compartmentalized GPCR Signaling: How Receptor Location Shapes Drug Responses

• Defining how signaling from the plasma membrane, endosomes and other intracellular compartments drives distinct biological outcomes
• Connecting compartmentalized GPCR signaling to downstream gene regulatory programs, neuronal remodeling and cellular adaptation
• Considering how spatial signaling principles may inform GPCR pharmacology and therapeutic selectivity

Speakers:

Nina Tsvetanova

Associate Professor - Pharmacology & Cancer Biology

Duke Office of Licensing & Ventures