Enabling DNA-Encoded Library Screening Against Challenging Peptide- Binding GPCR Targets

• Integrating reagent generation and tool compounds to establish screening-ready GPCR systems against peptide-binding receptors
• Applying biophysical and biochemical characterization approaches to improve confidence in target quality prior to screening
• Leveraging DEL technologies to identify novel small-molecule starting points against obesity-related GPCR targets

Speakers:

Ching-Hsuan Tsai

Executive Director, Head of Molecular Discovery

Structure Therapeutics