Engineering Agonism: A New Frontier in GPCR Antibody Discovery

1:10 pm - Thursday 30th April 2026

  • Unlocking state-specific GPCR conformations to move beyond binding-only generative models
  • Leveraging antibody agonists to precisely tune signaling bias in Class B GPCRs
  • Integrating epitope selection with full-molecule engineering for PK, delivery, and developability

Speakers:

Senior Scientist
Metaphore Biotechnologies