Christopher Roth

Senior Vice President - Research Abilita Therapeutics

Christopher Roth, PhD is the Senior Vice President of Research at Abilita Therapeutics, where he is leading multiple early therapeutic programs targeting GPCRs and ion channels for the treatment of cancer, cardiometabolic diseases and chronic pain. Prior to joining Abilita, Chris was a member of the founding scientific team at Receptos, where he invented novel GPCR engineering technologies that underpinned theUnlock structure-based discovery platform. Chris earned his PhD in the laboratory of Ray Stevens at The Scripps Research Institute, where he was a member of the team that solved seminal high-resolution GPCR crystal structures and developed core approaches used throughout the field today.

Seminars

Thursday 30th April 2026
Engineering GPCR Targets via Directed Evolution to Discover Pharmacologically Active Antibodies & Small-Molecule Modulators
9:00 am
  • Enabling the discovery of inverse agonist antibodies with the EMP directed evolution platform: shifting the paradigm for CCR8 therapeutics
  • Unlocking orphan receptors: discovery of inverse agonist small molecules to support target validation and therapeutic development
  • Evolving conformationally biased receptor antigens for the discovery of agonistic antibodies
Chris Roth