David o’connell
Associate Professor University College Dublin
David is an expert in protein engineering with a particular focus on development of novel therapeutic biologic molecules.
His research group specialises in phage display selection approaches, proteomic technologies, biophysical measurement of protein interactions with antibodies, small molecules and miniproteins. Their research into G Protein-Coupled Receptors (GPCRs) has led us to specialise further in nanodisc synthesis and Cryo-EM enabling capabilities.
He looks forward to exploring new collaborations in GPCR paradigms.
Seminars
Wednesday 3rd March 2027
Engineering Dual-Target & Multi-Receptor Therapeutics to Achieve Superior Clinical Outcomes
3:45 pm
- Enhancing efficacy through simultaneous modulation of complementary pathways
- Overcoming biological limitations associated with traditional single-target approaches
- Unlocking new opportunities through rational polypharmacology and multi-receptor design
