Hariprasad Vankayalapati
Chief Scientific Officer Biolexis Therapeutics
Hariprasad Vankayalapati, M. Pharm., PhD.
Hari co-founded Biolexis Therapeutics, Inc., where he serves as Chief Scientific Officer, overseeing the company’s R&D strategy across metabolic, cardiometabolic, oncology, and CNS therapeutic domains. In partnership with Dr. David J. Bearss, he co-developed the proprietary MolecuLern technology platform, which underpins Biolexis’s mission to discover and develop next-generation oral small-molecule therapeutics. Before founding Biolexis, Hari co-founded and led scientific functions at multiple biopharmaceutical ventures, advancing nine drug candidates into Phase I/II clinical evaluation. With more than two decades of experience spanning academia and industry, his career is defined by translational innovation and collaborative discovery. Hari also serves as a scientific advisor and review board member for pharmaceutical organizations and academic institutions. He earned his M.Pharm in Pharmaceutical Chemistry from the University of Karnataka and his PhD in Medicinal Chemistry from the Institute of Chemical Technology (formerly UDCT), University of Bombay, followed by postdoctoral research at the University of Sunderland, UK, and the University of Arizona Cancer Center under Professor Laurence H. Hurley. He has authored over 100 scientific publications and presentations and is an inventor on numerous issued and pending U.S. and international patents.
Seminars
- Discovering high-throughput and functional screening methods for identifying allosteric modulators
- How can we quantify efficacy, cooperativity, and pathway-specific modulation and use AI/ML to predict allosteric sites and optimize ligand properties?
- Case studies of allosteric GPCR modulators progressing to the clinic and how they’ve overcome side-effect profiles, exploited subtype selectivity and modulated complex signaling