Marcin Paduch

Marcin is the Head of Platform Biology at Metaphore. He is a trained structural biologist and protein engineer bringing a passion for blending multidisciplinary science and technology. Marcin has a long track record of innovation and has led diverse teams in high-impact research collaborations, formulating successful strategies for drug discovery campaigns, and fast-tracked preclinical development. He has developed several high-throughput, data-driven drug discovery platforms, ranging from biotherapeutics, including cell therapies, to small molecules. Before joining Metaphore Bio, Marcin served as an Executive Director at Xilis, where he developed workflows for drug screening and mechanism of action optimization in organotypic cell culture and patient-derived tumor organoids. Before that, he led technology development efforts at Arsenal Bio, the first programmable cell therapy company, advancing logic gate CAR-T programs through the clinic, System1 neuroscience startup developing therapeutics in cerebral organoid models reinventing neuro drug discovery, and Grail, where he worked on developing the Galeri multicancer early detection test, which is expected to dramatically improve the current paradigms of cancer diagnostics and management.
Before working in startups, Marcin spent nearly a decade as a director serving multiple industrial consortia and developing a portfolio of next-generation, antibody-based cancer therapies backed by major pharma companies. Marcin holds a PhD from the University of Wroclaw in biochemistry and molecular biology and a Master of Science in biotechnology.