Decoding the Molecular Basis of Biased Signalling at CB2 to Enable Rational Design of Next-Generation GPCR Ligands

10:45 am - Wednesday 3rd March 2027

  • Characterizing the molecular determinants of biased signalling at the CB2 receptor
  • Linking receptor conformational states to functional signalling outcomes to better understand GPCR ligand efficacy
  • Leveraging mechanistic insights to support the rational design of GPCR ligands with desired pharmacological profiles

Speakers:

Professor, Molecular & Cellular Pharmacology
University of Nottingham