Discovery of Clinical Candidate AZD5462, an Allosteric Oral Small Molecule Agonist for the Treatment of Heart Failure
Time: 9:30 am
day: Day Two AM
Details:
- Reviewing the optimization of small molecule agonists of the Relaxin Family Peptide Receptor (RXFP1) resulting in discovery of AZD5462
- Exploring mechanism of action and signaling in vitro and in vivo
- Demonstrating the efficacy of AZD5462 in non-human primates
