Fireside Chat: Overcoming Diversity in Therapeutic Outcomes by Elevating Bias Signaling

Time: 11:30 am
day: Day One Track A AM

Details:

  • How to leverage bias in candidate selection? How to identify the best signalling profile, and correlate cell signalling with efficacy?
  • What are the methods for revealing signaling bias for different G proteins? Understanding the preferential activation and recruitment of G protein and beta-arresting, respectively
  • Can we design biased ligands rationally? 
  • How to leverage AI to interpret data and inform drug design?

Speakers: