The Discovery of Alixorexton: Applying Structure-Guided Drug Design to Deliver a Selective Orexin 2 Receptor Agonist
1:30 pm - Tuesday 2nd March 2027
- Applying structure-guided design principles to optimize potency, selectivity and druglike properties
- Overcoming medicinal chemistry challenges associated with targeting the Orexin 2 receptor
- Translating receptor biology and pharmacology into a development candidate for narcolepsy
