Using Translational Techniques to Advance Next Generation 5-HT2A Agonists into the Clinic to Treat Depression
Time: 3:30 pm
day: Day Two AM
Details:
- Developing an optimized small molecule agonist of 5-HT2A receptors
- Utilization of biomarkers with high-translational value to guide dose selection for evaluating the safety and efficacy of small molecules targeting the CNS
- Reviewing 5-HT2A receptor binding in vitro, in vivo and the markers of target engagement from the bench to Phase I clinical trials
