Erik Hembre

Erik Hembre

Company: Eli Lilly & Co.

Job title: Assoc. Vice President


Pros & Cons of Positive Allosteric Modulation in GPCR Drug Discovery – Case Studies from Lilly Research Labs 11:30 am

Discussing the attributes of a target that make allosteric modulation a desirable MOA for drug discovery Importance of profiling and understanding the key parameters of allosteric modulation (affinity, alpha, and beta) and their impact on target product profile Emerging importance of GPCR structural biology in the design and optimization of allosteric modulatorsRead more

day: Day One Track B AM

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